The downloading of illicit content from the intern

first_imgThe downloading of illicit content from the internet in France is decreasing, while the consumption of legal content is growing, according to the latest survey by the Hadopi, the authority charged with implementing France’s antipiracy law.According to the survey, 78% of users now download legal content exclusively, , up from 71% in December 2011, while 15% use illegitimate sites, a lower proportion than previously. In total, 87% use legitimate sites. However, while the illicit consumption of music, images, video games and books has been decreasing, the consumption of TV shows and films is still giving cause for concern, with 21% admitting to accessing TV series from illicit sites and 24% accessing films and videos illicitly.last_img

Spains La Liga has introduced a new OTT TV servic

first_imgSpain’s La Liga has introduced a new OTT TV service that offers access to a range of minority sports from national sporting associations as well as second division football and summaries of La Liga matches.According to La Liga, the service, LaLigaSportsTV, which will – mostly – be available free-to-view, is intended as a way to distribute coverage of multiple sporting disciplines.The football league said that the service would provide a space for sports that are unavailable on traditional channels.La Liga said that the launch positioned it as the first major European league to roll out its own OTT TV service, offering a platform for niche sportsThe cloud-based service comes with a specially designed user interface and native apps, with content available in HD live and on-demand. LaLigaSports TV comes with a recommendation service based on usage patterns, as well as a scroll-based guide of available sports that is ordered according to user preferences over time.Individuals supporting the initiative include Javier Tebas, president of La Liga, José Hidalgo, president of the Asociación del Deporte Español (ADESP), Celestino García, the VP of corporate affairs at Samsung Electronics Iberia, Spain’s Rugby7 captain Paco Hernández and other sporting federation leaders.The service will be available via iOS and Android apps, Samsung smart TVs, Chromecast, Apple TV and Samsung streaming devices, with more web apps to follow.Content is available free of charge with the exception of second-tier football in the form La Liga 1|2|3, which is available for a separate subscription priced at €14.99 a year or €2.99 a month.Top tier football in the shape of La Liga Santander will not be available but match summaries will be broadcast along with pre- and post-match interviews.The service will include live coverage of sports such as motorsports, badminton, LEB Oro basketball, Liga ASOBAL handball, boxing, American football, Futsal, gymnastics, hockey, table-tennis, triathlon and water polo.Sports to follow later include cycling, petanque and fencing.last_img read more

Newly designed drugs could help combat any potential flu pandemic

first_imgReviewed by James Ives, M.Psych. (Editor)Jan 28 2019Researchers at LSTM and Imperial College London have designed drugs which could help combat any potential new flu pandemic, by targeting the receptors of the cells by which the virus gains entry to the human body.In a paper published today(link is external) in the Journal of Immunology the team, led by LSTM’s Professor Richard Pleass, show that by engineering a part of an antibody they can target the viral proteins that allow flu to mutate and become so deadly to humans.Last year marked the centenary of the 1918 influenza pandemic that claimed nearly 100 million lives worldwide, thus becoming the deadliest disease outbreak in recorded history. Global annual influenza outbreaks account for 300,000-650,000 respiratory deaths, mostly in children and the elderly.Related StoriesResearchers map virulence factor of influenza A virus in real-timeNaturally occurring human antibody reveals hidden weakness in influenza virusDrugs designed with advanced computing technologies could help tackle hospital superbugsProfessor Pleass explained: “Influenza vaccines have limited public health impact during pandemics, and current influenza vaccines are less efficacious than vaccines for many other infectious diseases. This is because influenza viruses that circulate in human and animal populations mutate two key viral surface proteins, haemagglutinin (HA) and neuraminidase (NA), thus allowing them to escape from protective antibodies produced through natural infection or vaccination”Both HA and NA target a sugar called sialic acid, that is found in abundance on the receptors of cells lining the mammalian respiratory tract, which the virus uses to gain entry into the body. The sialic acid-binding contacts on HA and NA do not mutate readily, otherwise the virus would not be able to infect human cells.The team has engineered antibody Fc fragments with enhanced sialic acid that target these conserved parts of both HA and NA, binding influenza viruses and thus blocking their interactions with human cells.By targeting sialic acid, these engineered biologicals may also be useful in the control of other pathogens, such as group B streptococci, Streptococcus pneumoniae, Mycoplasma genitalium, and Newcastle Disease Virus.”Better anti-influenza therapeutics are urgently needed.” Continued Professor Pleass: “The transfer of antibodies from people recovering from influenza during the 1918 and 2009 pandemics reduced mortality from influenza by 50% and 26% respectively. However, to be useful, these antibody medicines (also called FLU-IVIG) need to be manufactured in advance of future epidemics, which is obviously problematic as there may be modest or little neutralising activity against newly emerging strains. Therefore, combinations of existing medicines, including FLU-IVIG, with sialic acid blockers could increase their efficacy while future-proofing against the next pandemic.”Professor Sara Marshall, Head of Clinical and Physiological Sciences at the Wellcome Trust, who provided funding for this work, said: “This is a fascinating project, and one which could have really far-reaching impact not only for influenza but as a platform technology to develop new medicines for many other diseases that are currently treated by antibodies.”​ Source:https://www.lstmed.ac.uk/news-events/news/lstm-and-imperial-college-researchers-design-new-anti-influenza-drugslast_img read more

Gluten lactose food dyes in pills could be causing side effects finds

first_imgBy Dr. Ananya Mandal, MDMar 18 2019Pills or oral medications contain inactive ingredients. Some of these may be responsible for the side effects says a new study. The study results appeared in an article published in the latest issue of the journal Science Translational Medicine.The researchers explain that the allergic reactions to the pills may be due to inactive ingredients that make up the pill including lactose, gluten, food dyes etc. People who are allergic to these ingredients may experience worsening of their symptoms or allergic reactions. Image Credit: Pavel Kubarkov / Shutterstock Dr. Giovanni Traverso, from the department of gastroenterology at Brigham and Women’s Hospital and Harvard Medical School said that the results were surprising to the team of researchers. He was one of the authors of the study. He added, “. It involves almost every pill and capsule. And it’s something we tend not to think about.” Traverso is also part of the mechanical engineering department at MIT. He explained that the idea for this study came after a patient of Celiac disease presented with worsening of symptoms. The patient was not aware that the medication contained gluten, Traverso said and none of the prescribers were either. The team looked at other patients who had experienced similar side effects after taking the medication and found that several drug preparations could be harmful because of these seemingly innocuous ingredients.In 2017, the Food and Drugs Administration had prepared draft recommendations to label drug formulations that contained wheat derived products. The FDA also has a database with the list of all the inactive ingredients in prescription drugs.Daniel Reker, lead author of the study from Swiss National Science Foundation at Massachusetts Institute of Technology’s (MIT) Koch Institute for Integrative Cancer Research in Cambridge, Massachusetts, said, “For most patients, it doesn’t matter if there’s a little bit of lactose, a little bit of fructose, or some starch in there. However, there is a subpopulation of patients, currently of unknown size, that will be extremely sensitive to those and develop symptoms triggered by the inactive ingredients.”Related StoriesFeeling safe and good sleep at night matter most to sick kids in hospitalStudy analyzes high capacity of A. baumannii to persist on various surfacesBordeaux University Hospital uses 3D printing to improve kidney tumor removal surgeryThe team found that 44.82 percent of the pills contain lactose which can cause side effects among those who are lactose intolerant. Similarly 33 percent of the preparations contain food dyes. Around 3.8 percent of a study population was found to be allergic to a food dye called tartrazine. Complex sugars or FODMAPS (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols), in the pills are found in 55 percent drug formulations. This can lead to symptoms of bloating, gas, abdominal pain, constipation and diarrhea. These sugars in the pills can worsen symptoms of irritable bowel syndrome or IBS. Other ingrediets include corn starch in 36.54 percent pills, polyethylene glycol in 35.8 percent pills, povidone in 35.8 percent pills and carboxymethylcellulose in 21.38 percent pills. Some pills also contain wheat starch, artificial sweeteners, peanut oil etc. Traverso said, “Many probably have amounts that are low enough that they wouldn’t induce a reaction, but in patients taking more than one medication they might pose a problem. For example, lactose is in a significant proportion of medications.”Sravan Kumar Patel, a pharmaceutical chemist and an instructor of pharmaceutical sciences at the University of Pittsburgh Medical Center explained that the amount of these inactive ingredients is very small. He said, “If the required dose is 5 mg, that’s a really small amount and you can’t make a tablet out of that. So you mix it with an inactive ingredient such as lactose or dextrose and now you can make a tablet. It might not form into a tablet if you use something else.”Authors conclude in their study, “Recognizing that the inactive portion of a medication, which corresponds on average to two-thirds of the administered material, may be more ‘active’ than previously anticipated, we foresee potential implications for medical protocols, regulatory sciences, and pharmaceutical development of oral medications.”Source: http://stm.sciencemag.org/content/11/483/eaau6753last_img read more

PayPal buys payments startup iZettle for 22 bn

first_img © 2018 AFP PayPal buys money-sending service Xoom in $890 mn deal US-based PayPal, a unit of eBay, said that its biggest acquisition to date would strengthen its platform for handling payment transactions at small businesses, particularly in Europe and Latin America.”Small businesses are the engine of the global economy and we are continuing to expand our platform to help them compete and win online, in-store and via mobile,” PayPal chief executive Dan Schulman said in a release.”In today’s digital world, consumers want to be able to buy when, where and how they want.”Schulman described the merging of iZettle and PayPal as a “strategic fit” combining shared values and culture with complementary product offerings and geographies.The iZettle platform for handling retail transactions is used by nearly a half million merchants, according to PayPal.The startup has been compared to Square, a payments platform co-founded by Twitter chief executive Jack Dorsey that made it easy to take credit card payments using smartphones or tablets.Buying iZettle will expand PayPal’s reach into shops in Brazil, Denmark, Finland, France, Germany, Italy, Mexico, the Netherlands, Norway, Spain and Sweden.”Combining our assets and expertise with a global industry leader like PayPal allows us to deliver even more value to small businesses to help them succeed in a world of giants,” iZettle chief executive Jacob de Geer said in the release.The Stockholm-based startup founded in 2010 expected to handle about $6 billion in transactions this year, taking in gross revenue of approximately $165 million in the process. The company said it expects to reach profitability by the year 2020.After close of the acquisition, co-founder Jacob de Geer will remain in charge of iZettle, reporting to PayPal chief operating officer Bill Ready, according to the companies.Earlier this month, iZettle filed paperwork to go public with an offering of shares that valued the company at slightly more than a billion dollars.PayPal closed the Nasdaq trading day in New York with a market value of about $94 billion based on its share price, which rose a percent to $80 in after-hours trades. Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.center_img PayPal on Thursday announced a deal to buy Swedish online commerce startup iZettle for $2.2 billion, a deal that came as the young company was poised for a stock market debut. Citation: PayPal buys payments startup iZettle for $2.2 bn (2018, May 18) retrieved 18 July 2019 from https://phys.org/news/2018-05-paypal-payments-startup-izettle-bn.html US-based PayPal, a unit of eBay, has made its biggest acquisition to date by buying Swedish online commerce startup iZettle for $2.2 billionlast_img read more

Indiana Jones Meets Star Wars in Archaeology From Space Enter to Win

first_imgWhat is it like to uncover the mysteries of ancient civilizations … from space? Archaeologist Sarah Parcak is a pioneer in the field of space archaeology, using images from satellites orbiting high above Earth to detect long-buried signs of cultures that thrived millennia ago. Her work in Egypt resulted in a breakthrough map of the legendary city of Tanis, made famous in the movie “Raiders of the Lost Ark.” But while Parcak’s fictional counterpart Indiana Jones dug through dusty sand and crawled through jungles to reach remote sites, much of Parcak’s work is conducted on computers, analyzing images that use infrared and lasers to peer below the ground and reveal ancient secrets hidden far below.OTD in Space – July 17: X-15 Breaks Altitude RecordOn July 17, 1962, the American test pilot Bob White broke the world record for the highest altitude flight. He took off from Edwards Air Force Base in a rocket-powered X-15 aircraft and made it to an altitude of 314,750 feet. That’s almost 60 miles! At the time, the Air Force considered the edge of space to be 50 miles above the Earth. So White received astronaut wings for his record-breaking spaceflight.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放OTD in Space – July 16: Apollo 11 Launches to the Moon00:43关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65918-archaeology-from-space-giveaway.html?jwsource=cl已复制直播00:0000:3400:34  In Parcak’s new book “Archaeology from Space: How the Future Shapes Our Past” (Henry Holt and Company, 2019), she offers readers a tantalizing glimpse of the technologies that make space archaeology possible; she also reveals extraordinary discoveries that satellites have brought to the surface for the first time in thousands of years. Live Science sits down with Parcak on Facebook Live today (July 12) at 11:30 a.m. ET, for an interview about her book and her two decades of field work spanning five continents. We’ll also be giving away two copies of “Archaeology from Space” (one copy per winner). To participate, leave a comment on the post by 12:01 a.m on July 15. Winners will be selected at random. The contest rules are below. Don’t forget to check Facebook and Twitter for updates on this contest and other live-video events. ‘Archaeology From Space: How the Future Shapes Our Past’ Giveaway Official Rules NO PURCHASE NECESSARY. Open to legal residents of 50 U.S & D.C., 18 or older. Employees, agents, officers & directors of Future plc (“Sponsor”), its parent, subsidiaries, affiliates & advertising & promotion agencies (collectively with Facebook, Inc., “Released Parties”) & members of their immediate family (spouse, parent, children, siblings & their respective spouses, regardless of where they reside) & persons living in the same household, whether or not related, are not eligible. Void where prohibited. Subject to all applicable federal, state & local laws. HOW TO ENTER: At any time between 11:30 a.m. ET on Friday, July 12, 2019, and 12:30 a.m. ET on Monday, July 15, 2019 (the “Entry Period”), visit the Live Science page on Facebook (“Event Page”), find the post about the giveaway and leave a comment to the post. If, for whatever reason, the Event is cancelled or postponed, this giveaway will not occur. Entries generated by script, macro or other automated means or by any means that subvert the entry process are void. Limit one (1) entry per person/Facebook ID. Multiple entries will be void. Entries become the sole property of Sponsor. Entry must not be offensive or inappropriate, as determined by Sponsor in its sole discretion. Sponsor reserves the right to disqualify any entry and remove any comment that it determines, in its sole discretion, is not in compliance with these Official Rules or is otherwise not in keeping with Sponsor’s image. WINNER DETERMINATION: Three winners will be randomly selected from the eligible individuals who posted comments during the Entry Period. If, by the end of the Entry Period, no eligible comments are provided, the prize will not be awarded. Odds of winning depend on the number of eligible entries received. WINNER NOTIFICATION: Potential winners will be notified via a comment on his/her winning post and via Facebook Messenger & he/she will have 24 hours from notification to respond to Sponsor. The failure to respond to such notification or the potential winner’s noncompliance with these Official Rules may result in disqualification, & at Sponsor’s sole discretion, prize may be awarded to an alternate winner. Prize: A copy of “Archaeology From Space: How the Future Shapes Our Past” (2 prizes available). Approximate Retail Value: $30.00. Total Prize is awarded “as is” with no warranty or guarantee, either express or implied. Winner is responsible for all federal, state & local taxes. Winner may not substitute, assign or transfer prize, but Sponsor reserves the right, at its sole discretion, to substitute prize (or portion thereof) with one of comparable or greater value. Prize cannot be redeemed for cash. All prize details are at Sponsor’s sole discretion. GRANT OF RIGHTS: By submitting an entry, each entrant grants to Sponsor and its licensees, successors and assigns an irrevocable, perpetual, unlimited, royalty-free, fully paid-up license to reproduce, distribute, display, exhibit, exploit, perform, edit, create derivatives of, & otherwise use the entry & all elements of such entry, together with any other material, and the name, user name, city & state of residence, voice, image and/or likeness of entrant, in any & all media now known or hereafter devised, in any manner, in whole or in part, worldwide, without compensation or notification to, or permission from, entrant or any third party, for any purpose whatsoever, including without limitation, for purposes of advertising or trade.  CONDITIONS: By participating, each entrant agrees: (a) to abide by these Official Rules & decisions of Sponsor & judges, which shall be final & binding in all respects relating to this giveaway; and (b) to release, discharge & hold harmless Released Parties from any & all injuries, liability, losses & damages of any kind to persons, including death, or property resulting, in whole or in part, directly or indirectly, from entrant’s participation in the Giveaway or the acceptance or use of prize.  Released Parties are not responsible for (i) lost, late, incomplete, damaged, inaccurate, stolen, delayed, misdirected, undelivered or garbled entries; or (ii) errors or difficulties of any kind, whether human, mechanical, electronic, computer, network, typographical, printing or otherwise, relating to or in connection with the giveaway, including, without limitation, errors or difficulties which may occur in connection with the administration of the giveaway, the processing of entries, the announcement of the prize or in any giveaway-related materials.  Persons who tamper with or abuse any aspect of the giveaway or the Event Page, who act in an unsportsmanlike or disruptive manner or who are in violation of these Official Rules, as solely determined by Sponsor, will be disqualified & all associated entries will be void. Should any portion of the giveaway be, in Sponsor’s sole opinion, compromised by virus, worms, bugs, nonauthorized human intervention or other causes which, in the sole opinion of the Sponsor, corrupt or impair the administration, security, fairness or proper play, or submission of entries, Sponsor reserves the right at its sole discretion to suspend, modify or terminate the giveaway & if terminated, at its discretion, select winner as deemed fair & appropriate by Sponsor. Information submitted in connection with this giveaway will be used in accordance with Sponsor’s Privacy Policy, available at https://www.futureplc.com/privacy-policy/.   WINNERS’ NAMES: Winners’ names will be posted on the Event Page following the end of the giveaway.  Sponsor: Future plc, 11 West 42nd Street, 15th Floor, New York, New York 10036. This giveaway is in no way sponsored, endorsed or administered by, or associated with, Facebook. You understand that you are providing your information to Sponsor & not to Facebook. Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoSecurity SaversWindows Users Advised To Do This TodaySecurity SaversUndoArticles VallyDad Cuts Daughter’s Hair Off For Getting Birthday Highlights, Then Mom Does The UnthinkableArticles VallyUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoComparisons.org2019: Little-Known Rule in Rowland Heights, CAComparisons.orgKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndolast_img read more